Can you someone please explain the concept behind this.

Can you someone please explain the concept behind this. I’m more interested in learning how to approach the problem than the answer. How does the body weight of a person effect Vd values? And also, in the table where the Vd values are presented for each drug for example Drug A has a Vd = 16.0 + 4. What does the 4 mean? How do you interepret these values. I know it’s a lot of questions but I’m really stuck.

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The volume of distribution is the amount of drug in the body that means dose to the concentration of the drug distributed in the body that measured in blood, plasma, or tissue water. The concentration of the drug is the distribution of the drug in th…

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