Achondroplasia is a rare form of dwarfism caused by an autosomal dominant mutation that affects the gene that encodes a fibroblast growth factor receptor. Among 1,422,000 live births, the number of babies born with achondroplasia was 31. Among those 31 babies, 18 of them had one parent with achondroplasia. The remaining babies had two unaffected parents. How do you explain these 13 babies, assuming that the mutant allele has 100% penetrance? What are the odds that these 13 individuals will pass this mutant gene to their offspring?
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